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Erythropoietic protoporphyria treated with narrow‐band (TL‐01) UVB phototherapy
Author(s) -
Warren Lachlan J,
George Sheru
Publication year - 1998
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1998.tb01278.x
Subject(s) - erythropoietic protoporphyria , photosensitivity , medicine , dermatology , photodermatosis , optics , protoporphyrin , photochemistry , dna , chemistry , porphyrin , physics , genetics , xeroderma pigmentosum , biology , dna damage
SUMMARY Erythropoietic protoporphyria is a rare photodermatosis for which treatment options are limited. The present report describes the clinical features of a patient with erythropoietic protoporphyria and liver function test abnormalities associated with treatment with β‐carotene. Subsequent treatment with narrow‐band UVB phototherapy resulted in marked subjective improvement in photosensitivity, which was confirmed by abolition of demonstrated abnormalities on monochromator phototesting. The therapeutic options for photosensitivity in erythropoietic protoporphyria are reviewed and discussed.