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Disseminated sporotrichosis as a manifestation of immune reconstitution inflammatory syndrome
Author(s) -
GutierrezGalhardo Maria Clara,
Do Valle Antônio Carlos Francesconi,
Fraga Beatriz Lima Barros,
Schubach Armando Oliveira,
De Siqueira Hoagland Brenda Regina,
Monteiro Paulo César Fialho,
De Lima Barros Mônica Bastos
Publication year - 2010
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2008.01655.x
Subject(s) - sporotrichosis , medicine , immune system , immunology , immune reconstitution inflammatory syndrome , immunopathology , antiretroviral therapy , viral load , human immunodeficiency virus (hiv)
Summary We describe two cases of disseminated sporotrichosis as a manifestation of immune reconstitution inflammatory syndrome. After the initiation of highly active anti‐retroviral therapy, one patient presented disseminated lesions, whereas the other patient’s preexisting lesions worsened and became more extensive. Simultaneously, their CD4 T cell counts increased and HIV viral loads decreased.