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Anti‐ Malassezia furfur antibodies in the population
Author(s) -
Faggi Elisabetta,
Pini G.,
Campisi E.,
Gargani G.
Publication year - 1998
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.1998.tb00337.x
Subject(s) - antibody , population , malassezia , medicine , age groups , immunology , physiology , demography , dermatology , environmental health , sociology
Summary. The authors carried out research into anti‐ Malassezia precipitating antibodies in the population, specifying the distribution by age and sex. A total of 868 serum specimens from subjects of both sexes, aged between 0 and 80 years, were studied. An immunoelectroprecipitation reaction was used using a M. furfur culture filtrate as antigen. No antibodies were found in children under 11 years, whereas they were present after that age and reached maximum frequency in subjects between 31 and 40 years of age. In subjects up to 50 years of age they were more frequent in women, but in subjects over the age of 50 years they were more frequent in men. Globally, antibodies were found in 31% (270/868) of the subjects examined. The presence of antibodies correlates with data from the literature regarding the isolation of this yeast in relation to age. Zusammenfassung. Die Studie berichtet über den Nachweis präzipitierender Antikörper gegen Malassezia furfur in der Gesamtbevölkerung. Es wurden 868 Serumproben von Probanden beider Geschlechter im Alter zwischen 0 und 80 Jahren mittels Immunelektropräzipitation mit M. furfur ‐Kulturfiltrat als Antigen untersucht. Bei Kindern unter elf Jahren waren keine Antikörper nachweisbar. Antikörpernachweise erreichten ihr Häufig‐keitsmaximum in der Altersklasse von 31 bis 40 Jahren. Bei den unter Fünzigjährigen waren Antiörper häufiger bei Frauen, im Alter darüber häufiger bei Männern zu finden. Insgesamt waren bei 31% der Probanden (270/868) Antikörper nachweisbar. Diese Befunde stimmen überein mit Literaturangaben über die Hefeisolierung in Abhängigkeit vom Alter.

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