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An insertion/deletion in the porcine FGFR2 gene
Author(s) -
Aldenhoven J.,
Spötter A.,
Distl O.
Publication year - 2007
Publication title -
journal of animal breeding and genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.689
H-Index - 51
eISSN - 1439-0388
pISSN - 0931-2668
DOI - 10.1111/j.1439-0388.2007.00629.x
Subject(s) - genetics , mendelian inheritance , gene , biology , chromosome , microbiology and biotechnology
Summary The 7000‐rad INRA‐University of Minnesota porcine Radiation Hybrid panel was used to localize the FGFR2 gene on Sus scrofa chromosome 14 (SSC14). An insertion/deletion mutation of approximately 240 bp was detected in the porcine FGFR2 gene. This mutation consists of a repeat motif of 48 bp. In a short and long variant of this polymorphism, the motif was repeated either six or 11 times. The mutation was shown to follow a Mendelian mode of inheritance in 10 families including 48 pigs of Large White × Duroc origin.