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Notulae seminologicae. 8. ultrastructural sperm defects in two men, carriers of autosomal inversion
Author(s) -
Baccetti B.,
Collodel G.,
Crisa‘ D.,
Moretti E.,
Piomboni P.
Publication year - 2009
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/j.1439-0272.1997.tb00482.x
Subject(s) - ultrastructure , sperm , chromosomal inversion , biology , anatomy , inversion (geology) , andrology , pathology , medicine , karyotype , genetics , chromosome , gene , paleontology , structural basin
Summary The electron microscopical analysis of spermatozoa in two infertile male carriers of a pericentric inversion in one of the chromosomes 9 revealed the presence of a peculiar defect affecting the tails' fibrous sheath in both patients. This structure appeared completely disorganized and hyperplasic; sometimes the defect was associated with other usual malformations concerning the nuclear and acrosomal shape and texture and the axonemal assembly. Most spermatozoa (90–100%) of these patients were immotile. Our findings point to a definite ultrastructural sperm defect found in cases of autosomal inversion.