Open AccessAllo‐tolerance and allorejection responses ex vivo
Author(s) -
Moffatt S.D.,
Metcalfe S.
Publication year - 2000
Publication title -
transplant international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 82
eISSN - 1432-2277
pISSN - 0934-0874
DOI - 10.1111/j.1432-2277.2000.tb02087.x
Subject(s) - ex vivo , medicine , spleen , stat , immune system , in vivo , immune tolerance , immunology , intracellular , microbiology and biotechnology , biology , signal transduction , stat3
Spleen cells from fully immune competent mice show different intracellular STAT responses to alloantigen. Cells from mice primed to accept the alloantigen have low STAT 6 and fragmented STAT 4, compared to cells from mice primed to reject the same alloantigen.