Open AccessHeart transplantation for radiation‐associated end‐stage heart failure
Author(s) -
Handa Nobuhiro,
McGregor Christopher G. A.,
Daly Richard C.,
Dearani Joseph A.,
Edwards Brooks S.,
Frantz Robert P.,
Olson Lyle J.,
Rodeheffer Richard J.
Publication year - 2000
Publication title -
transplant international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 82
eISSN - 1432-2277
pISSN - 0934-0874
DOI - 10.1111/j.1432-2277.2000.tb01058.x
Subject(s) - medicine , sequela , malignancy , heart transplantation , transplantation , radiation therapy , stage (stratigraphy) , heart failure , heart disease , cardiology , surgery , paleontology , biology
Radiation‐induced heart disease is an increasingly recognized late sequela of mediastinal radiation therapy for malignant neoplasms. We report four cases of heart transplantation for end‐stage heart failure induced by mediastinal radiation therapy. Short‐term and intermediate‐term results are excellent with all four patients currently surviving a mean of 48 months after transplantation. Neither a second malignancy nor recurrence of the primary malignancy has been observed to date. The early results of heart transplantation for end‐stage, radiation‐induced heart disease are encouraging.