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Rh Blood Group Mosaicism in a Healthy Elderly Woman
Author(s) -
Salaru Nativa N. R.,
Lay Waltraut H.
Publication year - 1985
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1985.tb00197.x
Subject(s) - peripheral blood , chromosome , red cell , genetics , red blood cell , phenotype , biology , population , blood cell , immunology , andrology , medicine , physiology , gene , environmental health
Abstract. One example of Rh blood group mosaicism showing a mixed cell population of CcDe and cde red blood cells was found in tests on 552 normal individuals aged 60 years or more. The mosaic person was uninformative for other chromosome 1 markers having the phenotypes Fy (a–b+), 6‐PGD A and PGM 1 1 . Dosage of the activity of intraerythrocytic ENO‐1 and 6‐PGD of both cell populations fell in the normal range. Chromosome studies on peripheral lymphocytes did not reveal abnormalities. No definite conclusion could be drawn on the mechanism responsible for the phenomenon.