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The Titre of IgG Anti‐A/B in the Serum of Group O Mothers of Incompatible Infants with Early Neonatal Jaundice
Author(s) -
Luca E. Carapellade,
Pacioni C.,
Tonelli C.
Publication year - 1976
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1976.tb02813.x
Subject(s) - jaundice , exchange transfusion , titer , medicine , group b , coombs test , cord blood , group a , antibody , gastroenterology , immunology , pediatrics
Abstract. The titre of IgG anti‐A/B was determined by means of a 2‐mercaptoethanol test in the serum of 80 blood group O mothers, who gave birth at term to A/B incompatible infants, who developed early neonatal jaundice with a serum bilirubin level of over 10 mg/100 ml. The titres were compared with the results of the direct antiglobulin test performed on the red cells from the cord blood and the necessity for exchange transfusion. Only in mothers of group A infants, a significant correlation was found between the titre of IgG anti‐A and the occurrence of a positive antiglobulin test. In no case the need for an exchange transfusion was correlated with the IgG anti‐A/B titre.