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Anti‐Fy5, an Antibody Disclosing a Probable Association between the Rhesus and Duffy Blood Group Genes
Author(s) -
Colledge Katharine I.,
Pezzulic Marisa,
Marsh W. L.
Publication year - 1973
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1973.tb02630.x
Subject(s) - antibody , red blood cell , biology , blood type (non human) , gene , rh blood group system , immunology , microbiology and biotechnology , genetics , abo blood group system
Abstract. A new antibody, anti‐Fy5, has been found in the serum of a Negro Fy(a–b–) person. It reacts with Fy(a+) or Fy(b+) red cells of common Rh type, but not with Fy(a–b–) cells from Negroes, or with Rh null cells. An example of Caucasian Fy(a–b–) red cells was Fy5 positive. U‐negative or LW‐negative red cells give the reaction expected of their Duffy type. The data suggest that the Fy5 determinant is formed by interaction of Rhesus and Duffy gene products.