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Nitric Oxide Therapy
Author(s) -
Zapol
Publication year - 1996
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1996.tb04579.x
Subject(s) - medicine , nitric oxide , citation , library science , computer science
Zapol, W.M. Massachusetts General Hospital, Boston, MA 021 14 USA The major objective of this lecture is to describe the effects of inhaling low levels of nitric oxide (NO) on the hemodynamic and gas exchange function of both the normal and diseased lung. Considerable attention will be paid to safety and hazards of inhaled NO therapy. During the past few years remarkable progress has been made in understanding the NO-guanylate cyclase signal transduction system. NO has been given considerable clinical investigation in pulmonary artery hypertension and the adult respiratory distress syndrome (ARDS) patients. This lecture concentrates on this area of clinical research.