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Recurrence of Respiratory Depression Following Neurolept Analgesia
Author(s) -
Nilsson C.,
Rosberg B.
Publication year - 1982
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1982.tb01762.x
Subject(s) - medicine , fentanyl , narcotic , depression (economics) , respiratory system , anesthesia , analgesic , scoliosis , surgery , economics , macroeconomics
Fentanyl, though generally regarded as a short‐acting narcotic analgesic, can give unexpected respiratory depression several hours after the last dose. This potentially very dangerous effect is explained in pharmacokinetic studies by a mobilisation of fentanyl from tissue stores. In this report we describe a patient who, following a Harrington correction for scoliosis done with neurolept analgesia, developed a severe respiratory depression 5 h after the last dose of fentanyl.