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Placental p , p ′‐dichlorodiphenyldichloroethylene and cord blood immune markers
Author(s) -
Brooks Kevin,
Hasan Hanem,
Samineni Sridhar,
Gangur Venu,
Karmaus Wilfried
Publication year - 2007
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1111/j.1399-3038.2007.00546.x
Subject(s) - medicine , cord blood , placenta , immune system , cord , endocrinology , immunology , pregnancy , fetus , biology , surgery , genetics
Placental p , p ′‐dichlorodiphenyldichloroethylene ( p , p ′‐DDE) concentration and cord blood atopic markers were determined in 19 neonates. Increased placental p , p ′‐DDE was associated with a statistically significant increase in cord plasma interleukin (IL)‐13. Furthermore, both cord plasma IL‐4/interferon (IFN)‐ γ and IL‐13/IFN‐ γ ratios were significantly positively associated with placental p , p ′‐DDE concentration.