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Dual kidney transplantation after liver transplantation: a good option to rescue a patient from dialysis
Author(s) -
Ekser Burcin,
Furian Lucrezia,
Baldan Nicola,
Amico Alessandra,
Fabris Luca,
Lazzarin Manuela,
Marchini Francesco,
Rigotti Paolo
Publication year - 2009
Publication title -
clinical transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 76
eISSN - 1399-0012
pISSN - 0902-0063
DOI - 10.1111/j.1399-0012.2008.00903.x
Subject(s) - medicine , nephrotoxicity , transplantation , dialysis , calcineurin , liver transplantation , kidney transplantation , kidney , nephrology , urology , economic shortage , surgery , intensive care medicine , linguistics , philosophy , government (linguistics)
Abstract: Chronic renal failure (CRF) due to calcineurin inhibitor (CNI) nephrotoxicity is one of the most serious side effects influencing mortality and morbidity after liver transplantation (LTx). One way to offer a longer survival and better quality of life to LTx recipients who develop CRF is kidney transplantation, though this is not feasible for all candidates due to the shortage of organs. With changes in the characteristics of the global donor pool, which includes increasing number of elderly donors, both kidneys from one older donor are transplanted into the same adult recipient (dual kidney transplantation, DKT) to offset the lower nephron mass. DKT might be an option after LTx to rescue a patient from dialysis, with consequent survival benefits. We report on two cases of DKT after LTx in patients with CRF who were on dialysis due to CNI nephrotoxicity.