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The cis‐configuration effects of rare chromosomal fragile sites
Author(s) -
Côté Gilbert B.
Publication year - 1990
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1990.tb03532.x
Subject(s) - genetics , chromosome engineering , biology , chromosome , chromosomal fragile site , gene
Rare chromosomal fragile sites may adversely affect specific alkies of closely linked genes when in cis‐configuration. This is illustrated by data published in Sutherland & Hecht (1985) on chromosome 16 at band q22.1.