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The female and the fragile X syndrome: data on clinical and psychological findings in 7 fra(X) carriers
Author(s) -
Borghgraef M.,
Fryns J. P.,
Berghe H.
Publication year - 1990
Publication title -
clinical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 102
eISSN - 1399-0004
pISSN - 0009-9163
DOI - 10.1111/j.1399-0004.1990.tb03516.x
Subject(s) - fragile x syndrome , fragile x , shyness , anxiety , psychology , clinical psychology , developmental psychology , medicine , psychiatry , biology , genetics , gene
In this report we present precise data on the clinical, intellectual and behavioural findings in 7 young fra(X) positive girls. The two most common and most important findings are an overgrowth syndrome present from birth on and common behavioural features like severe attentional problems and extreme shyness and anxiety. These symptoms seem to constitute the major criteria for fra(X) screening in prepubertal girls. The findings in previous studies are compared with the present observations.