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Delayed hypersensitivity to bosentan
Author(s) -
Romano A.,
Giovannetti A.,
Caruso C.,
Rosato E.,
Pierdominici M.,
Salsano F.
Publication year - 2009
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.2008.01927.x
Subject(s) - medicine , bosentan , classics , dermatology , history , receptor , endothelin receptor
This is the first case of a cell-mediated hypersensitivity to bosentan diagnosed on the basis of positive responses to the lymphocyte transformation test and a challenge. However, the latter provoked a severe reaction (DRESS