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Betahistine‐induced bronchospasm
Author(s) -
Jiménez I.,
Antón E.,
Picáns I.,
Jerez J.
Publication year - 1996
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1111/j.1398-9995.1996.tb04585.x
Subject(s) - bronchospasm , betahistine , medicine , anesthesia , dermatology , asthma , surgery , vertigo
Betahistine is a cerebral vasodilator structurally related to histamine, which stimulates H 1 bronchial and vascular receptors. We report the case of a 28‐year‐old female patient who presented bronchospasm during treatment with betahistine hydrochloride. The prick test was negative. The oral challenge test showed bronchospasm and urticarial lesions. To the best of our knowledge, this is the first case of betahistine‐induced bronchospasm reported in the literature. The study carried out failed to reveal the mechanism of the reaction.