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Relapsing polychondritis in a child with common variable immunodeficiency
Author(s) -
Karaca Neslihan Edeer,
Aksu Guzide,
Yildiz Basak,
Gulez Nesrin,
Turk Bengu,
Dereli Tugrul,
Kutukculer Necil
Publication year - 2009
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1111/j.1365-4632.2009.03809.x
Subject(s) - relapsing polychondritis , medicine , chondritis , common variable immunodeficiency , autoimmunity , immunology , arthritis , polyarthritis , autoimmune hemolytic anemia , autoimmune disease , evans syndrome , dermatology , antibody
Common variable immunodeficiency (CVID) is associated with recurrent infections and autoimmunity. The most common autoimmune conditions are idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, chronic arthritis, and gastrointestinal inflammation. Relapsing polychondritis (RP) is an episodic and progressive systemic inflammatory disease, characterized by auricular chondritis, polyarthritis, nasal, and respiratory tract chondritis. Autoimmunity to cartilage‐related components is thought to be involved in its pathogenesis. So far, RP has not been included within many autoimmune conditions that have been reported in patients with either CVID or any other primary immunodeficiency. In this report, a case of CVID with RP and chronic arthritis is presented.