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Antigen‐Trapping Cells in Peyer's Patches of the Rat
Author(s) -
SMINIA T.,
JANSE E. M.,
WILDERS M. M.
Publication year - 1982
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1982.tb00749.x
Subject(s) - germinal center , follicular dendritic cells , antigen , spleen , microfold cell , lymph , lymph node , biology , pathology , lymphatic system , immunology , antigen presenting cell , b cell , antibody , t cell , medicine , immune system
Peyer's patches (PP) of rats were studied with immunocytochemical, enzyme cytochemical, and electron microscopic techniques. Special attention was paid to the non‐lymphoid antigen‐trapping cells. Follicular dendritic cells, morphologically comparable to those present in spleen and lymph nodes, were found in the germinal centers of PP. la‐positive cells with the morphological characteristics of interdigitating cells were seen in the interfollicular area. Thus, both types of antigen‐presenting cells, characteristic for B‐ and T‐cell areas, respectively, were present in PP.