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B‐L Antigens (Ia‐like Antigens) of the Chicken Major Histocompatibility Complex
Author(s) -
CRONE M.,
JENSENIUS J. CHR.,
KOCH C.
Publication year - 1981
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1981.tb00600.x
Subject(s) - antigen , biology , major histocompatibility complex , immune system , histocompatibility , homology (biology) , mixed lymphocyte reaction , pan t antigens , genetics , immunology , gene , microbiology and biotechnology , antibody , human leukocyte antigen , t cell , monoclonal antibody
This paper reviews the present knowledge of B‐L antigens encoded by the chicken B complex as regards to the following aspects: (1) identification and cellular expression, (2) structural studies, (3) evidence for two distinct populations of B‐L antigens, (4) mapping of B‐L loci of the B complex, (5) B‐L and immune response, and (6) the role of the B‐L antigens for the control of mixed lymphocyte reactions (MLR) and graft‐versus‐host (GVH) reactions. It is concluded that B‐L antigens of the chicken exhibit extensive homology with mammalian la antigens. A genetic map of the B complex is presented.