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In Vitro Enhancement of Natural Cytotoxicity by Tumour Necrosis Serum
Author(s) -
PASANEN V. J.
Publication year - 1979
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1979.tb01351.x
Subject(s) - cytotoxic t cell , cytotoxicity , in vitro , necrosis , tumor necrosis factor alpha , immunology , biology , pathology , medicine , biochemistry
Cells cytotoxic for syngeneic, allogeneic and xenogeneic cultured target cells are shown to be induced spontaneously in cultures of murine lymphoid cells. Serum containing bacillus Calmette‐Guérin and endotoxin‐induced tumour necrosis factor accelerates the appearance of observed natural cytotoxic cells.