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Studies on the Induction of Antibody Synthesis against Sulfanilic Acid in Rabbits.
Author(s) -
RUBIN B.
Publication year - 1972
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1111/j.1365-3083.1972.tb00591.x
Subject(s) - sulfanilic acid , antibody , conjugate , serum albumin , chemistry , antigen , bovine serum albumin , immunology , biology , biochemistry , mathematics , organic chemistry , mathematical analysis
The present experiments (carried out in rabbits) have demonstrated that antibodies directed against new antigenic determinants introduced in rabbit serum albumin (RSA) through the coupling with sulfanilic acid (Sulf) were able to enhance (or‘help’) a primary antibody response to Sulf 11 RSA. This enhancement phenomenon was shown to be specific for Sulf‐carrier conjugates.