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PAIRED HELICAL FILAMENTS IN RAT SPINAL GANGLIA FOLLOWING CHRONIC ALCOHOL ADMINISTRATION: AN ELECTRON MICROSCOPIC INVESTIGATION *
Author(s) -
VOLK B.
Publication year - 1980
Publication title -
neuropathology and applied neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.538
H-Index - 95
eISSN - 1365-2990
pISSN - 0305-1846
DOI - 10.1111/j.1365-2990.1980.tb00285.x
Subject(s) - neuropathology , electron microscope , anatomy , spinal cord , ethanol , chemistry , medicine , pathology , biology , neuroscience , physics , biochemistry , disease , optics
Volk B. 1980 Neuropathology and Applied Neurobiology 6, 143–153 Paired helical filaments in rat spinal ganglia following chronic alcohol administration: an electron microscopic investigation Youang Wistar rats were given a 15% (v/v) ethanol solution ad libitum for at least 6 months, spinal ganglia (C6–7 and Ll‐2) in some of the experimental animals showed paired helical filaments. These curvilinear profiles consisted of 10 nm filaments with the twist every 35nm. There was also an increase in granular material and in nematosomes. Whether these features may be caused by an impaired cerebral protein biosynthesis is discussed.