Premium
Functional analysis of the fsoC gene product of the F7 1 ( fso) fimbrial gene cluster
Author(s) -
Riegman N.,
Acton D.,
Sakkers R.,
Die I.,
Hoekstra W.,
Bergmans H.
Publication year - 1990
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/j.1365-2958.1990.tb02018.x
Subject(s) - biology , biogenesis , gene cluster , mutant , gene , protein subunit , cluster (spacecraft) , fimbria , genetics , microbiology and biotechnology , escherichia coli , computer science , programming language
Summary Contrary to what would be expected from data in the literature, mutations in the fsoC gene of the F7 1 ( fso) P‐fimbrial gene cluster do not completely block fimbrial biogenesis. fsoC mutants still express small amounts of fimbriae of normal length, which carry the non‐adhesive minor subunit protein, FsoE, but lack the adhesin, FsoG. The FsoC protein operates at the same stage in fimbrial biogenesis as the FsoF and FsoG proteins. The data suggest that FsoC, FsoF and FsoG interact to form an initiation complex for fimbrial biogenesis.