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Pharmacokinetics and anthelmintic efficacy of febantel in the racing pigeon (Columba livia)
Author(s) -
BAERT L.,
POUCKE S. VAN,
VERMEERSCH H.,
REMON J. P.,
VERCRUYSSE J.,
BASTIAENSEN P.,
BACKER P. DE
Publication year - 1993
Publication title -
journal of veterinary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.527
H-Index - 60
eISSN - 1365-2885
pISSN - 0140-7783
DOI - 10.1111/j.1365-2885.1993.tb00167.x
Subject(s) - capillaria , anthelmintic , veterinary medicine , clearance , medicine , biology , helminths , immunology , urology
This paper reports on the pharmacokinetics and the efficacy of febantel against Capillaria obsignata and Ascaridia columbae in the racing pigeon. Febantel was rapidly cleared from the circulation and highly metabolized. The efficacy of febantel against Capillaria and Ascaridia was studied on lightly and heavily infected pigeons. The efficacy against Ascaridia was 100% for the faecal egg count reduction (FECR) as well as for the worm reduction in all treated pigeons. After two treatments with febantel against Capillaria in heavily infected pigeons the FECR amounted to 96.7% and worm reduction was 95%. In order to effectively remove both parasites from the host, repeated treatments with febantel at a short interval could be the treatment of choice.