Premium
The determination of propiopromazine in animal tissue
Author(s) -
OLLING M.,
STEPHANY R. W.,
RAUWS A. G.
Publication year - 1981
Publication title -
journal of veterinary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.527
H-Index - 60
eISSN - 1365-2885
pISSN - 0140-7783
DOI - 10.1111/j.1365-2885.1981.tb00865.x
Subject(s) - phenothiazine , residue (chemistry) , tissue distribution , chemistry , kidney , chromatography , veterinary medicine , pharmacology , biology , endocrinology , medicine , biochemistry
A thin‐layer chromatographic method for the determination of the veterinary tranquillizer propiopromazine (Combelen®) in slaughter pigs is described. Propiopromazine residue depletion from the kidney occurs with different rates in sows and in castrated boars. In the liver residues increase over at least 24 h after intramuscular administration, in accordance with the distribution pattern of phenothiazine tranquillizers.