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Morphometric studies on mouse bone using a computer‐based image‐analysis system
Author(s) -
Green D.,
Howells G. R.,
Thorne M. C.
Publication year - 1981
Publication title -
journal of microscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 111
eISSN - 1365-2818
pISSN - 0022-2720
DOI - 10.1111/j.1365-2818.1981.tb01241.x
Subject(s) - transverse plane , femur , anatomy , vertebra , chord (peer to peer) , anisotropy , materials science , biomedical engineering , physics , biology , optics , medicine , computer science , paleontology , distributed computing
SUMMARY The morphological structure of the ilium, femur, third lumbar vetrebra and a central caudal vertebra of the female CBA mouse has been studied using 5 μm thick, plastic embedded, transverse and longitudinal sections. The sections were analysed on a Quantimet 720, system 30, image analyser connected on‐line to a PDP11 computer. Separate endosteal and periosteal surface to volume ratios were calculated for each position of sampling in each bone. For this calculation the anisotropy of the bone was estimated from measurements of mean chord lengths in longitudinal sections of the bone using a new analytical technique. Chord length distributions in transverse sections of bone were also measured and the relevance of such measurements to the study of morphological changes in the bone and its included marrow are briefly discussed.