Premium
Surgical treatment of corneal pathology in patients with Down's syndrome
Author(s) -
VÖLKERDIEBEN H. J.,
ODENTHAL M. T. P.,
D'AMARO J.,
KRUIT P. J.
Publication year - 1993
Publication title -
journal of intellectual disability research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1111/j.1365-2788.1993.tb00584.x
Subject(s) - keratoconus , medicine , corneal transplantation , blindness , surgery , retrospective cohort study , transplantation , population , ophthalmology , cornea , optometry , environmental health
ABSTRACT Keratoconus is a major cause of blindness in patients with Down's syndrome. A retrospective study of 30 corneal grafts for keratoconus in these patients revealed a 5‐year graft survival of 67%. Postoperative trauma and/or infection was the main cause for graft failure. Conditions that should be met before the indication for corneal transplantation in a patient with Down's syndrome are formulated as a result of 15 years experience with that patient population. In appropriate cases, corneal transplantation may undoubtedly improve the quality of life in these patients.