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4‐Aminopyridine (fampridine) effectively treats amlodipine poisoning: a case report
Author(s) -
Wilffert B.,
Boskma R. J.,
Voort P. H. J. van der,
Uges D. R. A.,
Roon E. N. van,
Brouwers J. R. B. J.
Publication year - 2007
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1111/j.1365-2710.2007.00861.x
Subject(s) - amlodipine , 4 aminopyridine , 2 aminopyridine , calcium , medicine , anesthesia , chemistry , blood pressure , medicinal chemistry , potassium channel
Summary A case of a serious poisoning with the calcium entry blocker amlodipine is described, which was treated effectively with 4‐aminopyridine. Calcium is suggested as general treatment of poisoning with calcium entry blockers in many guidelines. The use of intravenous 4‐aminopyridine is theoretically useful to treat poisoning from calcium entry blockers and was demonstrated in this case report.