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A new screening method for investigating microbial interactions
Author(s) -
MacFarlane T.W.,
Makrides H.C.
Publication year - 1982
Publication title -
journal of applied bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 0021-8847
DOI - 10.1111/j.1365-2672.1982.tb04850.x
Subject(s) - effector , candida albicans , escherichia coli , agar , staphylococcus aureus , microbiology and biotechnology , biology , agar plate , chemistry , bacteria , food science , biochemistry , genetics , gene
Interactions among Candida albicans, Staphylococcus aureus and Escherichia coli were investigated using a screening system in which test micro‐organisms were incorporated in agar discs and effector micro‐organisms in fluid growth media. Total as well as partial inhibition of test micro‐organisms was observed in agar discs when these were incubated in broths containing effector micro‐organisms. The ratio of numbers of test to effector micro‐organisms was found to be of importance in the inhibition effect. The technique was found to be cheap, simple and versatile.