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Histogenesis of post‐mastectomy angiosarcoma—an ultrastructural study
Author(s) -
McWILIAM L. J.,
HARRIS M.
Publication year - 1985
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1985.tb02451.x
Subject(s) - histogenesis , angiosarcoma , pathology , staining , ultrastructure , metastasis , negative stain , immunohistochemistry , biology , electron microscope , medicine , cancer , physics , optics
An example of post‐mastectomy angiosarcoma was studied by electron microscopy to determine its histogenesis. Unequivocal evidence of endothelial differentiation was found in well and poorly differentiated areas. Positive staining for factor VIII related antigen and negative staining for epithelial membrane antigen further confirmed that the tumour was a true angiosarcoma rather than a peculiar form of carcinomatous metastasis.