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Clear cell sarcoma associated with multiple pulmonary metastases with structural and numerical karyotypic changes
Author(s) -
Kato N.,
Mizuno O.,
Tamura A.,
Yamanaka Y.,
Tanimura S.,
Minakawa H.
Publication year - 2004
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2004.01615.x
Subject(s) - chromosomal translocation , sarcoma , pathology , chromosome , karyotype , biology , metastasis , cytogenetics , clear cell sarcoma , cancer research , medicine , genetics , cancer , gene
Summary Cytogenetic analysis was performed on a specimen from a pulmonary metastasis of clear cell sarcoma originated on the right ankle of a 53‐year‐old Japanese woman. It revealed near‐triploid with several numerical changes including abnormalities in the copy number of chromosomes 7, 8, and 22, and structural abnormalities of chromosome 22 and others. This is a minor case which showed the multiple abnormalities of chromosomes in the absence of a t (12;22) translocation.