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Scleroderma and the taxanes. Is there really a link?
Author(s) -
Farrant P. B. J.,
Mortimer P. S.,
Gore M.
Publication year - 2004
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.2004.01519.x
Subject(s) - scleroderma (fungus) , medicine , chemotherapy , dermatology , oncology , immunology , inoculation
Summary Scleroderma has been associated with exposure to many substances in the past ranging from vinyl chloride to silicon dioxide. In recent years there have been a number of case reports linking modern chemotherapy agents, such as the taxanes to the development of scleroderma like changes. We present a further case of scleroderma in association with chemotherapy but question the role of some of the agents previously implicated. A brief review of the current literature is included.