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Multiple warty dyskeratomas of the scalp
Author(s) -
GRIFFITHS T.W.,
HASHIMOTO K.,
SHARATA H.H.,
ELLIS C.N.
Publication year - 1997
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1997.tb01059.x
Subject(s) - scalp , pathology , keratin , immunohistochemistry , outer root sheath , biology , human skin , lesion , staining , monoclonal antibody , antibody , medicine , anatomy , immunology , genetics
Summary Two patients presented with the unusual condition of multiple warty dyskeratomas on the scalp. Biopsies of affected skin stained positive with human keratin monoclonal antibodies HKN‐6 and ‐7, specific for cortex and inner root sheath of normal human hair, respectively. Multiple warty dyskeratomas are a rare occurrence and their actiopathogenesis remains elusive. Positive immunohistochemical staining of a lesion with antikeratin antibodies HKN‐6 and ‐7, specific for human hair keratin, suggests a follicular origin for warty dyskeratoma.