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Bullous pemphigoid—a report of 86 cases from Taiwan
Author(s) -
CHANG Y.T.,
LIU H.N.,
WONG C.K.
Publication year - 1996
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1111/j.1365-2230.1996.tb00005.x
Subject(s) - medicine , bullous pemphigoid , pemphigoid , prednisolone , incidence (geometry) , dermatology , blisters , direct fluorescent antibody , immunofluorescence , indirect immunofluorescence , complete remission , gastroenterology , surgery , antibody , chemotherapy , immunology , physics , optics
Summary We reviewed 86 cases of bullous pemphigoid and the results were compared with those reported in rhc literature. Seventy‐eight per cent of the patients developed generalized blisters and 22% hntl localized blisters, including three cases of dyshidrosiform pemphigoid and one case of pretibial pemphigoid. Oral mucosal involvement was noticed in 12.8% of the patients, Fifteen per cent of the patients had internal malignancies but the incidence was not significantly different from the control group. Direct immunofluorescence in our series showed a high positive rate of 98‐8%. Indirect imniunofluorescenee was positive in 48.1% of the 54 patients in whom this was carried out. Peripheral blood eusinophilia was observed in 221% of rhe patients. Prednisolone alone or in combination with immunosuppressive agents was the mainstay of treatment. Treatment side‐effects was observed in 33% of the patients. Thirty percent of the patients had a complete remission after a mean follow‐up period of 269 months.