Epidermolysis bullosa acquisita associated with chronic lymphatic leukaemia | Zendy

SHAW MARCIA | Zendy; McKEE P.H. | Zendy; GAMINARA ELIZABETH | Zendy; PEARSON T.C. | Zendy; EVANS BERYL | Zendy; McGIBBON D.H. | Zendy

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Epidermolysis bullosa acquisita associated with chronic lymphatic leukaemia

Author(s) -

SHAW MARCIA,

McKEE P.H.,

GAMINARA ELIZABETH,

PEARSON T.C.,

EVANS BERYL,

McGIBBON D.H.

Publication year - 1985

Publication title -

clinical and experimental dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.587

H-Index - 78

eISSN - 1365-2230

pISSN - 0307-6938

DOI - 10.1111/j.1365-2230.1985.tb00546.x

Subject(s) - epidermolysis bullosa acquisita , dermoepidermal junction , medicine , pathology , immunoelectron microscopy , dermatology , lymphatic system , epidermolysis bullosa , pathogenesis , immunology , bullous pemphigoid , antibody , dermis , immunohistochemistry

Summary A 61–year‐old man developed epidermolysis bullosa acquisita (EBA) in association with an IgM paraprotein and chronic lymphatic leukaemia (CLL). Direct immunocyto‐chemistry and immunoelectron microscopy confirmed the presence of IgM at the dermoepidermal junction. IgG was not present. This appears to be a unique observation in EBA and is discussed in relationship to the possible pathogenesis of the disorder.

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