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Environmental epigenetics and allergic diseases: recent advances
Author(s) -
Kuriakose J. S.,
Miller R. L.
Publication year - 2010
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.2010.03599.x
Subject(s) - epigenetics , immunology , allergy , disease , asthma , epigenesis , medicine , biology , dna methylation , genetics , gene expression , pathology , gene
Significant strides in the understanding of the role of epigenetic regulation in asthma and allergy using both epidemiological approaches as well as experimental ones have been made. This review focuses on new research within the last 2 years. These include advances in determining how environmental agents implicated in airway disease can induce epigenetic changes, how epigenetic regulation can influence T helper cell differentiation and T regulatory cell production, and new discoveries of epigenetic regulation associated with clinical outcomes. Cite this as : J. S. Kuriakose and R. L. Miller, Clinical & Experimental Allergy , 2010 (40) 1602–1610.