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Atopy and cystic fibrosis
Author(s) -
REEN D. J.,
CARSON J.,
MAGUIRE O.,
FITZGERALD M. X.,
TEMPANY E.
Publication year - 1981
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1111/j.1365-2222.1981.tb02177.x
Subject(s) - atopy , cystic fibrosis , sibling , medicine , allergy , immunology , dermatology , psychology , developmental psychology
Summary We have investigated the prevalence of atopy within families of cystic fibrosis (CF) patients and compared its frequence in CF patients, their parents and their non‐CF siblings. By studying families with two CF patients it was also possible to evaluate the factors influencing the development of atopy in one CF patient relative to the other patient within the same family. A significant correlation with age ( P < 0.001) for skin test positivity to common allergens within CF sibling pairs was observed. In 14/18 families studied, only the older CF patient was atopic. The presence of atopy in CF patients was independent of the atopic status of their parents.