Mites and house dust allergy III.  In vitro  lymphocyte transformation and precipitating antibody to house dust and mite ( Dermatophagoides pteronyssinus ) extract in atopic and non‐atopic individuals | Zendy

ROMAGNANI S. | Zendy; BILIOTTI G. | Zendy; PASSALEVA A. | Zendy; RICCI M. | Zendy

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Mites and house dust allergy III. In vitro lymphocyte transformation and precipitating antibody to house dust and mite ( Dermatophagoides pteronyssinus ) extract in atopic and non‐atopic individuals

Author(s) -

ROMAGNANI S.,

BILIOTTI G.,

PASSALEVA A.,

RICCI M.

Publication year - 1973

Publication title -

clinical and experimental allergy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.462

H-Index - 154

eISSN - 1365-2222

pISSN - 0954-7894

DOI - 10.1111/j.1365-2222.1973.tb01309.x

Subject(s) - immunology , house dust mite , mite , allergy , antibody , in vitro , counterimmunoelectrophoresis , biology , immunoglobulin e , medicine , ecology , biochemistry

Summary In vitro lymphocyte transformation and the precipitating antibody to house dust and mite ( Dermatophagoides pteronyssinus ) extract were studied in mite‐ and house‐dust sensitive patients and in non‐atopic individuals. House‐dust extract was able to induce a significant [2‐ 14 C]thymidine incorporation into lymphocytes from house‐dust‐sensitive as well as non‐allergic individuals. An in vitro response to mite extract, even if less marked, was also seen in most of mite‐sensitive patients. By the micro‐Ouchterlony and counterimmunoelectrophoresis techniques anti‐dust antibodies were found in the serum of all house‐dust‐sensitive and non‐atopic individuals tested. Anti‐mite precipitins were detected in a smaller number of subjects.

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