Open AccessMitotic Rate of Rat Thyroid Follicular Cells In Vivo In Response to A Single Injection of Thyrotropin (Tsh)
Author(s) -
Redmond Olga,
Tuffery A. R.
Publication year - 1981
Publication title -
cell proliferation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.647
H-Index - 74
eISSN - 1365-2184
pISSN - 0960-7722
DOI - 10.1111/j.1365-2184.1981.tb00847.x
Subject(s) - in vivo , mitosis , thyroid , medicine , endocrinology , thyrotropin receptor , follicular phase , biology , chemistry , microbiology and biotechnology , graves' disease , genetics
The mitotic rate of thyroid follicular cells was assessed by a stathmokinetic method at intervals from 15 min to 24 hr after a single injection of 1 iu/kg of thyrotropin (TSH). the mitotic rate was increased 15 min after TSH and remained elevated for 3 hr. Two further peaks of mitotic activity were present at 9 hr and 24 hr after TSH. Serum TSH concentrations were increased from 5 min to 3 hr with a maximum at 1 hr.