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Delayed hypersensitivity to one low‐molecular‐weight heparin with tolerance of other low‐molecular‐weight heparins
Author(s) -
BIRCHER A.J,
ITIN P.H,
TSAKIRIS D.A,
SURBER C.
Publication year - 1995
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1995.tb08684.x
Subject(s) - low molecular weight heparin , heparin , medicine , sensitization , subcutaneous injection , adverse effect , anesthesia , pharmacology , surgery , immunology
Summary We report a patient who developed infiltrated plaques at the sites of subcutaneous injection of a low‐molecular‐weight heparin. Skin tests and a lymphocyte transformation test revealed hypersensitivity to sandoparin and heparin sodium. The low‐molecular‐weight heparins nadroparin and dalteparin were subsequently tolerated without adverse effects. Possible risk factors for sensitization are discussed.