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A rare presentation of acantholytic dyskeratosis
Author(s) -
HAYAKAWA K.,
NAGASHIMA M.
Publication year - 1995
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1995.tb02685.x
Subject(s) - acantholysis , dyskeratosis , dermatology , presentation (obstetrics) , pathology , biopsy , scalp , medicine , histology , dyskeratosis congenita , skin biopsy , hyperkeratosis , biology , surgery , dna , genetics , telomere , antibody , immunology , autoantibody
Summary We describe an elderly woman who presented with numerous papular, keratolic lesions on the scalp. Histology of a biopsy specimen revealed epidermal invaginations, with large keratotic plugs, at the sites of hair follicles. In addition, there was acantholytic epidermal cell separation at a suprabasal level, and a large number of corps ronds were present, above the split. It is likely that this case represents a rare presentation of acantholytic dyskeratosis. The relationship to other conditions which show acanlholysis and dyskeratosis histologically is discussed.