Churg–Strauss syndrome

Churg–Strauss syndrome is a rare diffuse vasculitis that is closely associated with a severe asthma. The clinical diagnosis may be difficult in the early stages. Nevertheless, the onset of severe asthma in an adult and the emergence of extrarespiratory manifestations should alert one to the probable diagnosis of Churg–Strauss syndrome. Imaging is useful to assess the cardiorespiratory system and the sinus cavities. Pathological confirmation can be challenging as the characteristic histological features are often incomplete. Prognosis is usually good with corticosteroid therapy alone or in combination with immunosuppressive drugs.