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Failure of terfenadine in relieving the pruritus of atopic dermatitis
Author(s) -
BERTHJONES J.,
GRAHAMBROWN R.A.C.
Publication year - 1989
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1989.tb08196.x
Subject(s) - terfenadine , atopic dermatitis , placebo , medicine , dermatology , allergy , visual analogue scale , anesthesia , immunology , alternative medicine , pathology
SUMMARY We report the results of a double‐blind, placebo‐controlled, cross‐over study of terfenadine 120 mg twice daily for pruritus in atopic dermatitis. Twenty‐eight subjects with chronic atopic dermatitis received both terfenadine 120 mg b.d. and placebo each for a period of 1 week. Response was recorded by the subjects using visual analogue scales for severity of pruritus twice daily for the last 4 days of each treatment phase. There was no benefit from terfenadine.