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The effect of captopril on cutaneous blood flow in patients with primary Raynaud's phenomenon
Author(s) -
RUSTIN M.H.A.,
ALMOND N.E.,
BEACHAM J.A.,
BROOKS R.J.,
JONES D.P.,
COOKE E.D.,
Dowd P.M.
Publication year - 1987
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1987.tb07356.x
Subject(s) - captopril , medicine , placebo , double blind , blood flow , raynaud disease , cardiology , dermatology , blood pressure , pathology , alternative medicine
summary Fifteen patients with primary Raynaud's phenomenon received captopril 25 mg or placebo, three times daily for 6 weeks, in a randomized double‐blind cross‐over study. Compared with placebo, captopril produced a significant improvement in cutaneous blood flow but did not alter the frequency or severity of attacks of Raynaud's phenomenon.