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Thymic hypoplasia, auto‐immune haemolytic anaemia and juvenile pemphigoid in an infant
Author(s) -
BLOOMFIELD SUSAN,
STOCKDILL G.,
BARNETSON R.StC.
Publication year - 1982
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1982.tb01735.x
Subject(s) - immune system , medicine , autopsy , hypoplasia , juvenile , immunology , antibody , pathology , biology , genetics
SUMMARY A female infant developed auto‐immune haemolytic anaemia and juvenile pemphigoid, and died at the age of 10 months. Autopsy showed evidence of thymic hypoplasia and T lymphocyte deficiency. It was concluded that the two rare auto‐immune diseases occurring in this child probably resulted from a lack of T cell regulation of antibody‐producing B lymphocytes.