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The epidermal cell kinetics of the erythrokeratodermas
Author(s) -
RALFS I.,
DAWBER R. P. R.,
RYAN T. J.,
WRIGHT N. A.
Publication year - 1982
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1982.tb00407.x
Subject(s) - kinetics , vincristine , cell growth , cancer research , cell , biology , chemistry , medicine , microbiology and biotechnology , biochemistry , chemotherapy , physics , quantum mechanics , cyclophosphamide
SUMMARY The cell proliferation kinetics of the genodermatoses, erythrokeratoderma variabilis (EKV) and symmetrical progressive erytbrokeratoderma (SPE), were studied using flash labelling studies and cell production rates using vincristine. In EKV the results indicated a mildly hyperproliferative state, while in SPE the results, although variable, showed a prominent epidermal hyperproliferation.