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An immunofluorescence study of pityriasis lichenoides
Author(s) -
CLAYTON ROGER,
HAFFENDEN GERALD
Publication year - 1978
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1978.tb02015.x
Subject(s) - immunofluorescence , pityriasis , dermatology , medicine , immunology , antibody
SUMMARY In a Study of 27 patients with pityriasis lichenoides IgM and C 3 have been observed on direct immunofluorescence of fresh lesions. Other immunoglobulins and complement components were not observed. Immunofluorescence was seen in 31 (72%) of 43 fresh lesions. It occurred in the walls of superficial dermal vessels and along the dermal‐epidermal junction. This pattern of immunofluorescence appears to be characteristic of the disease. Uninvolved skin showed the immunofluorescence less frequently and old scaly lesions none. The concept that pityriasis lichenoides is an immune complex disorder is discussed.