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CORTICOSTEROID‐INDUCED ATROPHY OF THE SKIN WITH TELANGIECTASIA
Author(s) -
STEVANOVIC DANILO V.
Publication year - 1972
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1972.tb07444.x
Subject(s) - dermatology , telangiectasia , medicine , atrophy , corticosteroid , surgery , pathology
Summary.— Six patients with corticosteroid‐induced atrophy of the skin with telangiectasia are recorded and are briefly discussed. The skin changes were produced experimentally in 3 volunteers by prolonged topical application of “Synalar forte” and studied with light and electron‐microscopy, It is suggested that the first changes in the dermal tissue occur in the ground substance, followed by those of elastic and collagen fibres. These changes are ascribed mainly to the incomplete inhibition of fibroblasts by the corticosteroid.